Labels:text | screenshot | black | black and white | font | document OCR: teroids is thus Biosynthesis of the adrenoco rious steroid effected by the interaction of 50 C17ow, and hydroxylases: P450 scc, P450 C steroid P450 C11B. In addition, 3ß-hy ed to change the dehydrogenase isomerase is r t 4-ene-3-one structure in ring A to the im be capable only of configuration. P450 C21 appe xample, of 17- effecting hydroxylation at C2 rtisol), whereas hydroxyprogesterone to 11-de onal. Thus, P450 other hydroxylases are multi C22, and also scc effects hydroxylation at C2 iates acts as a 20,22 lyase, P450 C17c as a 17,20 lyase. hydroxylation at C17cv and al ha glomerulosa This enzyme is absent from t c capacity of the on, P450 C11 cells, which limits the steroid hd C19, and can cells to mineralocorticoid pro causes hydroxylation at C11, ( atase. also act in some species as ...
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